Pharm. D. Syllabus (Hamdard University) : Pharm. D. 3rd Prof. 2nd Semester

Pharm. D. Third Professional

Second Semester

Pharmaceutical Chemistry

Instrumentation and Analysis – II (Theory)

PHC-502                                                                                                                      Cr. Hrs. 3

1.      Spectroscopic Methods

1.1.  Atomic Absorption and Emission Spectroscopy

1.2.  Flame Photometry

1.3.  l.R, Spectroscopy

1.4.  Mass Spectroscopy

1.5.  N.M.R. Spectroscopy

1.6.  U.V./Visible Spectroscopy

1.7.  X-ray Spectroscopy

2.      Chromatographic Methods

2.1.  Thin Layer Chromatography

2.2.  Column Chromatography

2.3.  Gas Liquid Chromatography

2.4.  High Performance Liquid Chromatography

2.5.  GC-MS

Pharmaceutical Chemistry

Instrumentation and Analysis (Lab)

PHC-504                                                                                                                      Cr. Hrs. 2

Note : Practicals of the subject shall be designed from time to time on the basis of the topics covered in theory and availability of the requirements, e.g. Determination of the Purity and Composition of the unknown drugs by using at least each of the techniques covered in theory.

Pharmaceutics

Computer and its Applications in Pharmacy (Lab)

PHT-506                                                                                                                      Cr. Hrs. 2

1.      Introduction to Microsoft Windows and its different packages like Word, Excel, Power Point, etc.

2.      Internet and E-mail

2.1.  Internet and Microsoft Internet Explorer 5

2.2.  Addresses, Links and Downloading

2.3.  Searching the Internet

2.4.  E-mail and Newsgroups

2.5.  Favorites, security and Customizing Explorer

3.      Web Page Development

3.1.  Introduction to Front-page

3.2.  Creating a First Web site

3.3.  Basic Formatting Techniques

3.4.  Manipulating Tables within Front-page

3.5.  Front-page, Picture and Multimedia

3.6.  Hyper linking, Bookmarks and Image Maps

3.7.  Introducing Front-page "components"

3.8.  Front-page and Frames

3.9.  Managing your Web

3.10. Good site design. Publishing and Publicizing

4.      Complete Statistical Package like SPSS

5.      Languages: At least two prevailing languages will be taught

Pharmaceutics

Community Pharmacy (Theory)

PHT-508                                                                                                                      Cr. Hrs. 3

1.      Definitions and Background

2.      Public Health and Community Pharmacy

2.1.        Epidemiology & its Control

2.2.        Preventive Health (EP1 & CDC)

2.3.        Family Planning

2.4.        Health Policy & National Drug Policy

3.      Patient Assessment

4.      Medical Complication of Drug Taking

4.1.1.    General

4.1.2.    Socioeconomic Aspects

5.      Patient-Pharmacist Communication

6.      Patient Education and Councelling

7.      Control of Drug Abuse and Misuse

8.      Role of Pharmacist as Public Health Educator in the Community for Drug Monitoring and Drug Information.

Pharmacognosy

Chemical Pharmacognosy – I (Theory)

PHG-510                                                                                                                      Cr. Hrs. 3

1.      Separation and isolation of plant constitutions

1.1.  An introduction to chromatography and chromatographic techniques e.g.

1.1.1.     Adsorption Chromatography.

1.1.2.     Partition Chromatography

2.      Carbohydrates

2.1.  Introduction of carbohydrates,

2.1.1.     Sucrose and Sucrose containing drugs:

2.1.1.1.    Sucrose, Dextrose, Liquid glucose, Fructose, Lactose, Xylose, Caramel, Honey, Starch, Inulin, Dextrin etc.

2.1.2.     Cellulose and Cellulose Derivatives:

2.1.2.1.    Purified cotton. Powdered cellulose, Microcrystalline cellulose, Methyl cellulose, Sodium Carboxy-methyl cellulose.

2.1.3.     Gums and. Mucilages:

2.1.3.1.    Tragacenth, Acacia, Sodium Alginate, Agar, Pectin.

3.      Glycosides:

3.1.  Introduction, classification, chemistry and medicinal uses of:

3.1.1.     Cardioactive glycosides:

3.1.1.1.    Digitalis, Strophanthus and white squill.

3.1.2.     Anthroquinone qlvcosides:

3.1.2.1.    Cascara, Aloe, Rhubarb, Cochineal and Senna.

3.1.3.     Saponin glycosides:

3.1.3.1.    Glycyrrhiza, Sarsaparilla.

3.1.4.     Cyanophore glycosides:

3.1.4.1.    Wild cherry.

3.1.5.     Isothiocyanate glycosides:

3.1.5.1.    Black Mustard

3.1.6.     Lactone glycosides:

3.1.6.1.    Cantharide.

3.1.7.     Aldehyde glycosides:

3.1.7.1.    Vanilla.

3.1.8.     Miscellaneous glycosides:

3.1.8.1.    Gentian, Quassia, Dioscorea.

4.      Tannins

4.1.  Introduction, classification, properties and chemical identity tests. Detailed study of:

4.1.1.  Hamamelis

4.1.2.  Catechu

4.1.3.  Nut Galls.

5.      Lipids

5.1.  Introduction, Detailed study of:

5.1.1.     Fixed Oils:

5.1.1.1.   Castor oil, Cotton Seed oil, Olive oil, Peanut oil, Sun Flower oil, Corn oil, Coconut oil, Almond oil, Linseed oil, Mustard oil, Sesame oil and Soybean oil

5.1.2.     Fats and Related Compounds:

5.1.2.1.   Theobroma oil and Lenolin,

5.1.3.     Waxes:

5.1.3.1.   Bees wax, carnauba wax, spermaceti, Jojoba oil.

Pharmacognosy

Chemical Pharmacognosy (Lab)

PHG-512                                                                                                                      Cr. Hrs. 2

1.      Extraction of the active constituents of crude drugs and chemical tests for their identification.

2.      Isolation and separation of active constituents of crude drugs by paper and thin layer chromatography

Pharmacology

Systemic Pharmacology – III (Theory)

PHL-514                                                                                                                      Cr. Hrs. 3

1.      Chemotherapy

1.1.  Antiprotozoals

1.1.1.     Treatment of Malaria

1.1.2.     Treatment of Amebiasis

1.1.3.     Treatment of Trypanosomiasis

1.1.4.     Treatment of Leishmaniasis

1.1.5.     Treatment of Toxaplasmosis

1.1.6.     Treatment of Giardiasis

1.2.  Antibacterials

1.2.1.     Folate Antagonists

1.2.1.1.     Folate Synthetase Inhibitors

1.2.1.2.     Folate Reductase Inhibitors

1.2.2.     Cell Wall Synthesis Inhibitors

1.2.2.1.     Penicillinins

1.2.2.2.     Cephalosporins

1.2.2.2.1.         Fist Generation Cephalosporins

1.2.2.2.2.         Second Generation Cephalosporins

1.2.2.2.3.         Third Generation Cephalosporins

1.2.2.3.     Carbapenems

1.2.2.4.     Monobactams

1.2.2.5.     Miscellaneous (Vancomycin, Bacitracin, etc.)

1.2.3.     β-Lactamase Inhibitors

1.2.4.     Protein Snthesis Inhibitors

1.2.4.1.     Tetracyclines

1.2.4.2.     Aminoglycosides

1.2.4.3.     Macrolides

1.2.4.4.     Chloramphenicol

1.2.4.5.     Clindamycin

1.2.5.     Quinolones

1.2.6.     Urinary Tract Antiseptics (Nitrofurantoin, Methenamine).

1.2.7.     Antimycobacterial Drugs

1.2.7.1.     Anti-tuberculosis Drugs

1.2.7.2.     Anti-leprosy Drugs

1.3.  Antiviral Drugs

1.4.  Antifungals

1.5.  Anthelmintics

1.6.  Anti-neoplastic and Immunosuppressive drugs

2.      Hormones, Antagonists and other agents affecting Endocrine Function

2.1.  Endocrine function and dysfunctions

2.2.  Drug used for therapy of Diabetes Mellitus

2.2.1. Insulins

2.2.2. Oral Hypoglycemic agents

2.3.  Corticosteroids

2.4.  Thyroid hormone and antithyroid drugs

3.      Toxicology

3.1.  Pollution and its typers (water, air, food)

3.2.  Poison and principle of poisoning treatment.

3.2.1. Antidotes

3.3.  Signs & Symptoms and Treatment of Poisoning by

3.3.1. Ethanol

3.3.2.       Barbiturates

3.3.3.       Digitalis

3.3.4.       Salicylides

3.3.5.       Strychnine

3.3.6.       Narcotics

3.3.7.       Nicotine

3.3.8.       Paracetamol

3.3.9.       Benzodiazepines

3.3.10.   Organophosphorous compounds

3.4.  Chelating agents and their role in poisoning.

3.4.1.       Dimercaprol

3.4.2.       Calcium disodium edetate

3.4.3.       Pencillamine

3.4.4.       Desfroxamine

Pharmacology

Pharmacology (Lab)

PHL-516                                                                                                                      Cr. Hrs. 2

1.      To study the convulsant effects of strychnine and picrotoxin in frogs and to determine the site of action.

2.      To identify the unknown (convulsant) drug and determine its site of action.

3.      To study the effects of Adrenaline on Human Eyes.

4.      To study the effects of Pilocarpine on Human Eyes.

5.      To study the effect of Homatropine on Human Eyes.

6.      To identify and observe the effects of unknown drugs on Human Eyes.

7.      To study the effects of local anaesthetic drugs on human and the nerve plexus of frog.

8.      To identify and differentiate the effects of unknown drug on human and the nerve plexus of frog.

9.      To demonstrate the effects of Acetylcholine on the Rectus abdominus muscle of frog and competitive pharmacological antagonism by Neuromuscular blocking agent e.g., Gallamine.

10. To study the anti-coagulant effects of Heparin and oral anti-coagulants on Rabbits.

11. To identify the unknown drug by performing pharmacological competitive antagonism on Rectus abdominus muscle of Frog.

12. To demonstrate the graded Dose-Response curve of Acetylcholine on Rabbit intestine.

13. To identify unknown concentration of Acetylcholine from graded Dose-Response curves.